The ability to anticipate future ischemic events in the brain is the goal of CAIN1. This presentation given by Josephine Pressacco for Alan Moody, covers the hypothesis, rationale, methods, goals and status of the CAIN1 project as of April 2011. Building on work already accomplished, it is anticipated that high resolution MRI will be proven useful in predicting end organ ischemic events through detailed characterization of atherosclerotic plaques.