Understanding the markers of atherosclerosis is pivitol to providing effective care and perhaps prevention of the disease in others. Currently, upwards of 50% of patients with atherosclerosis first present to clinical medicine after a critical event. Dr. Larsose describes what is currently known and what steps are being taken to understand important disease targets including effective characterization of plaque morphology. It is our goal to prove imaging as an invaluable tool in improving patient outcomes.